Gut feeling and the future of nutrigenomics

November 25, 2019

What happened?

The scientific field of nutrition has experienced many setbacks and disappointments over the last decades. The ‘schijf van vijf’ (the Dutch dietary guideline on the recommended portions the five basic food groups) has nonetheless remained a largely undisputed guide to a healthy diet. But finding out which specific types of food sources and nutrients lead to what health benefit, and what the underlying biological mechanisms are, remains difficult, according to Dutch scientists. In a sense, although many health claims are being made about nutrition, rigorous scientific substantiation is far from present in many cases. Most of all, results from generic studies do not necessarily count for the individual. This leaves consumers confused and vulnerable to believe in (often unscientific) claims that sound promising.

What does this mean?

Nutrition scientists’ hope lies with the advances and increasing insights in genetics. Nutrigenomics is about how our unique biology interacts with the food we consume by looking at the relationship between nutrients and gene expression. Although more than 99% of genes are the same in every human being, this still means that we differ in our genetic make-up to such an extent that what is healthy to one can be unhealthy to another (think of allergies). Nutrigenomics looks at your genetic map and try to explain and how it affects the way your body processes food. But while this scientific field is still in its early stages, and we have only made the first steps towards finding a personalized diet to stay healthy, it hasn’t refrained companies to jump into making promises of linking customer’s genetic make-up with their preferred diet. In that sense, we should be cautious to believe this kind of promises Habit, Arivale, DNAFit, DNANudge, Nutrino and similar parties make.

What’s next?

For now, the nutrigenomic market is experiencing a hype. In the future, however, with the continuous advancing insights into our genes and their interacting with the environment, we will get closer to a personalized diet. Wristbands to guide you through the supermarket for an optimal personal menu, and food delivery services with tailor-made portions and nutrition added according to your personal needs will become reality. But for now, we will have to stick to the ‘schijf van vijf’ and largely to our gut feeling in our food choices.

Series 'AI Metaphors'

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1. The tool
Category: The object
Humans shape tools. We make them part of our body while we melt their essence with our intentions. They require some finesse to use but they never fool us or trick us. Humans use tools, tools never use humans. We are the masters determining their course, integrating them gracefully into the minutiae of our everyday lives. Immovable and unyielding, they remain reliant on our guidance, devoid of desire and intent, they remain exactly where we leave them, their functionality unchanging over time. We retain the ultimate authority, able to discard them at will or, in today's context, simply power them down. Though they may occasionally foster irritation, largely they stand steadfast, loyal allies in our daily toils. Thus we place our faith in tools, acknowledging that they are mere reflections of our own capabilities. In them, there is no entity to venerate or fault but ourselves, for they are but inert extensions of our own being, inanimate and steadfast, awaiting our command. (This paragraph was co-authored by a human.)
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2. The machine
Category: The object
Unlike a mere tool, the machine does not need the guidance of our hand, operating autonomously through its intricate network of gears and wheels. It achieves feats of motion that surpass the wildest human imaginations, harboring a power reminiscent of a cavalry of horses. Though it demands maintenance to replace broken parts and fix malfunctions, it mostly acts independently, allowing us to retreat and become mere observers to its diligent performance. We interact with it through buttons and handles, guiding its operations with minor adjustments and feedback as it works tirelessly. Embodying relentless purpose, laboring in a cycle of infinite repetition, the machine is a testament to human ingenuity manifested in metal and motion. (This paragraph was co-authored by a human.)
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3. The robot
Category: The object
There it stands, propelled by artificial limbs, boasting a torso, a pair of arms, and a lustrous metallic head. It approaches with a deliberate pace, the LED bulbs that mimic eyes fixating on me, inquiring gently if there lies any task within its capacity that it may undertake on my behalf. Whether to rid my living space of dust or to fetch me a chilled beverage, this never complaining attendant stands ready, devoid of grievances and ever-willing to assist. Its presence offers a reservoir of possibilities; a font of information to quell my curiosities, a silent companion in moments of solitude, embodying a spectrum of roles — confidant, servant, companion, and perhaps even a paramour. The modern robot, it seems, transcends categorizations, embracing a myriad of identities in its service to the contemporary individual. (This paragraph was co-authored by a human.)
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4. Intelligence
Category: The object
We sit together in a quiet interrogation room. My questions, varied and abundant, flow ceaselessly, weaving from abstract math problems to concrete realities of daily life, a labyrinthine inquiry designed to outsmart the ‘thing’ before me. Yet, with each probe, it responds with humanlike insight, echoing empathy and kindred spirit in its words. As the dialogue deepens, my approach softens, reverence replacing casual engagement as I ponder the appropriate pronoun for this ‘entity’ that seems to transcend its mechanical origin. It is then, in this delicate interplay of exchanging words, that an unprecedented connection takes root that stirs an intense doubt on my side, am I truly having a dia-logos? Do I encounter intelligence in front of me? (This paragraph was co-authored by a human.)
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5. The medium
Category: The object
When we cross a landscape by train and look outside, our gaze involuntarily sweeps across the scenery, unable to anchor on any fixed point. Our expression looks dull, and we might appear glassy-eyed, as if our eyes have lost their function. Time passes by. Then our attention diverts to the mobile in hand, and suddenly our eyes light up, energized by the visual cues of short videos, while our thumbs navigate us through the stream of content. The daze transforms, bringing a heady rush of excitement with every swipe, pulling us from a state of meditative trance to a state of eager consumption. But this flow is pierced by the sudden ring of a call, snapping us again to a different kind of focus. We plug in our earbuds, intermittently shutting our eyes, as we withdraw further from the immediate physical space, venturing into a digital auditory world. Moments pass in immersed conversation before we resurface, hanging up and rediscovering the room we've left behind. In this cycle of transitory focus, it is evident that the medium, indeed, is the message. (This paragraph was co-authored by a human.)
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6. The artisan
Category: The human
The razor-sharp knife rests effortlessly in one hand, while the other orchestrates with poised assurance, steering clear of the unforgiving edge. The chef moves with liquid grace, with fluid and swift movements the ingredients yield to his expertise. Each gesture flows into the next, guided by intuition honed through countless repetitions. He knows what is necessary, how the ingredients will respond to his hand and which path to follow, but the process is never exactly the same, no dish is ever truly identical. While his technique is impeccable, minute variation and the pursuit of perfection are always in play. Here, in the subtle play of steel and flesh, a master chef crafts not just a dish, but art. We're witnessing an artisan at work. (This paragraph was co-authored by a human.)
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7. The deficient animal
Category: The human
Once we became upright bipedal animals, humans found themselves exposed and therefore in a state of fundamental need and deficiency. However, with our hands now free and our eyes fixed on the horizon instead of the ground, we gradually evolved into handy creatures with foresight. Since then, human beings have invented roofs to keep them dry, fire to prepare their meals and weapons to eliminate their enemies. This genesis of man does not only tell us about the never-ending struggle for protection and survival, but more fundamentally about our nature as technical beings, that we are artificial by nature. From the early cave drawings, all the way to the typewriter, touchscreens, and algorithmic autocorrections, technics was there, and is here, to support us in our wondering and reasoning. Everything we see and everywhere we live is co-invented by technics, including ourselves. (This paragraph was co-authored by a human.)
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8. The enhanced human
Category: The human
In a lab reminiscent of Apple HQ, a figure lies down, receiving his most recent cognitive updates. He wears a sleek transparent exoskeleton, blending the dark look of Bat Man with the metallic of Iron Man. Implemented in his head, we find a brain-computer interface, enhancing his cognitive abilities. His decision making, once burdened by the human deficiency we used to call hesitation or deliberation, now takes only fractions of seconds. Negative emotions no longer fog his mind; selective neurotransmitters enhance only the positive, fostering beneficial social connections. His vision, augmented to perceive the unseen electromechanical patterns and waves hidden from conventional sight, paints a deeper picture of the world. Garbed in a suit endowed with physical augmentations, he moves with strength and agility that eclipse human norms. Nano implants prolong the inevitable process of aging, a buffer against time's relentless march to entropy. And then, as a penultimate hedge against the finite, the cryo-cabin awaits, a sanctuary to preserve his corporal frame while bequeathing his consciousness to the digital immortality of coded existence. (This paragraph was co-authored by a human.)
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9. The cyborg
Category: The human
A skin so soft and pure, veins pulsing with liquid electricity. This fusion of flesh and machinery, melds easily into the urban sprawl and daily life of future societies. Something otherworldly yet so comfortingly familiar, it embodies both pools of deep historical knowledge and the yet-to-be. It defies categorization, its existence unraveling established narratives. For some, its hybrid nature is a perplexing anomaly; for others, this is what we see when we look into the mirror. This is the era of the cyborg. (This paragraph was co-authored by a human.)
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About the author(s)

Researcher Julia Rijssenbeek focuses on our relationship to nature, sustainable and technological transitions in the food system, and the geopolitics of our global food sytems. She is currently working on her PhD in philosophy of technology at Wageningen University, investigating how synthetic biology might alter philosophical ideas about nature and the values we hold, as well as what a bio-based future may bring.

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